Product name: 4-Nitrobenzyl hydrogen malonate
Appearance: White to Slight yellow Powder
Boiling Point: 455.8°C at 760 mmHg
Packaging Details: According to the customer's requirements.
4-Nitrobenzyl hydrogen malonate is used to synthesize meropenem and meropenem is an artificial broad-spectrum carbapenem antibiotic, which produces antibacterial effect by inhibiting the synthesis of bacterial cell wall. Meropenem easily penetrates the cell walls of most gram-positive and negative bacteria and reaches its target of penicillin binding protein (PBPS). With the exception of metal β -lactamases, the hydrolysis of most β -lactamases (including penicillin and cephalosporinase produced by Gram-positive and Gram-negative bacteria) was stable. Meropenem is not suitable for the treatment of methicillin-resistant staphylococci infection, and sometimes cross resistance to other carbapenem resistant strains. In vitro experiments showed that meropenem combined with aminoglycoside antibiotics could produce synergistic effects on some strains isolated from Pseudomonas aeruginosa.
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