Product name:Cilastatin acid
Synonyms:(2Z)-7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic Acid; MK-791;
Appearance:White to Light Yellow Solid
Melting Point:>144ºC (dec.)
Applications:Cilastatin prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. It is an antibacterial adjunct.
Place of origin: Xinxiang China
Description:Cilastatin is an inhibitor of dipeptidase (dehydropeptidase I), a renal dipeptidase.1 It inhibits human renal dipeptidase (Ki = 0.7 μM), porcine dipeptidase (IC50 = 0.11 μM), and bacterial metallo-β-lactamase CphA from A. hydrophila (IC50 = 178 μM).1,2,3 Cilastatin (200 μg/ml) protects primary porcine renal proximal tubular epithelial cells from nephrotoxicity and apoptosis induced by vancomycin (Item No. 15327).4 In a mouse model of systemic infection, cilastatin in combination with imipenem (Item No. 16039) protects mice from S. aureus, E. coli, and P. aeruginosa infection.5 Cilastatin was designed to inhibit renal metabolism of imipenem and prolong its half-life.2 Formulations containing cilastatin in combination with imipenem have been used to treat susceptible bacterial infections.
a) Free sample can be supplied.
b) Guide our clients by professinal knowledge and teach them how to use our product after sales
c) Accpet SGS,BV any other third-party inspection before loading
d) High quality best price Guaranteed
e) Cooperate with research institutions, strictly quality control.
f) Reasonable price, high quality product and prompt shipment.
g) Send the goods to your delivery address directly by our factory.
h) Quick and clear response to customers questions.
Warm after-sale service, we will help to solve the problems in your usage.
i) We could make our price discount if you place a substantial order with us.
Q2: Which payment terms do you accept?
A2: L/C, T/T, D/A, D/P, Western Union, MoneyGram, Paypal are available.But different payment terms against countries.
Q3: What's about the MOQ ?
A3: It depends on different products.Usually our MOQ is 1kg.
Q4: What’s the delivery lead time?
A4: We will make delivery within 7 days after receiving payment.
Q5: What about the delivery port?
A5: Main ports in China are available.
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