- Jan 10, 2019 -
This product is a new carbapenem antibiotic, by binding to penicillin binding protein (PBP), it interferes with the synthesis of bacterial cell wall, resulting in the inhibition of bacterial growth and reproduction, and a few cells dissolve. This product has high antibacterial activity against methicillin-sensitive Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes and other gram-positive bacteria. Haemophilus, Mora, Neisseria meningitidis are highly sensitive, but resistant to methicillin-resistant Staphylococcus, Enterococcus, Pseudomonas aeruginosa and Acinetobacter. This product is stable to most penicillin, cephalosporinase and extended-spectrum-szlig;- lactamases, but can be hydrolyzed by metallozyme. The product is stable to human kidney dehydropeptidase-ⅰ and does not need combined use with cilastatin and so on.